Viekira Pak für die Behandlung von Hepatitis C-Infektionen

Bildnachweis: clinicaladvisor.com

What is Viekira Pak used for?

Viekira Pak is indicated for the treatment of adult patients with chronic hepatitis C virus (HCV) [see Dosage and Administration ( 2.2) and Clinical Studies ( 14 )]: genotype 1a without cirrhosis or with compensated cirrhosis for use in combination with ribavirin.

What is Viekira Pak (Vee Kee Rah Pak)?

Viekira Pak (vee kee' rah pak) is the commercial name for a combination of oral, direct acting antiviral agents used to treat chronic hepatitis C associated with HCV genotype 1.

Does Viekira Pak treat hepatitis C?

(Among 241 Italian patients with chronic hepatitis C, genotype 1, and cirrhosis treated with Viekira Pak with or without ribavirin for 12 to 24 weeks, the SVR rate was 95% and adverse events arose in 31% including 3 patients with hepatic decompensation, two with ascites and 1 with encephalopathy all of whom recovered and had an SVR).

What is the mechanism of action of Viekira Pak?

Viekira Pak combines three direct-acting hepatitis C virus antiviral agents with distinct mechanisms of action [see Microbiology ( 12.4 )]. Ritonavir is not active against HCV. Ritonavir is a potent CYP3A inhibitor that increases peak and trough plasma drug concentrations of paritaprevir and overall drug exposure (i.e., area under the curve).

What is Viekira Pak?

LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Last Update: February 7, 2022. Viekira Pak is a combination of oral antiviral agents that previously was used to treat chronic hepatitis C, genotype 1.

Was Ist Viekira Pak

1. https://www.aerzteblatt.de/nachrichten/64566/Viekirax-Toedliche-Leberschaeden-durch-Hepatitis-C-Kombination
2. https://www.ncbi.nlm.nih.gov/books/NBK548747/
3. https://www.drugs.com/mtm/viekira-pak.html
4. https://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540656/all/Viekira_Pak%E2%80%8B%E2%80%8B
5. https://www.hiv.gov/blog/fda-approves-viekira-pak-to-treat-hepatitis-c
6. https://www.medicine.com/drug/viekira-pak
7. https://link.springer.com/chapter/10.1007/7355_2018_60
8. https://www.hepatitiscentral.com/viekira-pak/what-is-viekira-pak/

Informationen Zu Viekira Pak

1. https://arznei-news.de/viekirax-bei-hepatitis-c/
2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/206619lbl.pdf
3. https://pubmed.ncbi.nlm.nih.gov/31644056/